276 research outputs found

    Assessment of Time and Costs of Two Formwork Methodologies in the Philippines using BIM Simulation

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    In the Philippine construction industry, choices of formwork methodology is critical to contractors or client/project managers. Cost and time are the parameters commonly considered to address which method is recommended for a project. In this study, simulation using BIM was made from input parameters taken from actual project observations and data collection from five projects. Two methods were considered: method A (traditional forms) and method B (steel decks). The output parameters after the BIM simulation were processed cost and time. A statistical t-test was conducted for both process costs and time durations to differentiate between the two methods. It was found out that the process costs for overall, columns, and beams of method A were not statistically different from method B, while the slab process cost was significantly different. This indicated that only slab process cost was relatively expensive for method B. For the duration, both the columns and beams were not statistically different, while overall and slabs’ duration was significantly different. It showed that overall duration and slab process duration is relatively lower for method B. This paper showed that BIM simulation could help managers in their decision on choosing the construction methodology to balance cost and time of their project

    Frequency dynamics of gain-switched injection-locked semiconductor lasers

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    The frequency dynamics of gain-switched singlemode semiconductor lasers subject to optical injection is investigated. The requirements for low time jitter and reduced frequency chirp operation are studied as a function of the frequency mismatch between the master and slave lasers. Suppression of the power overshoot, typical during gain-switched operation, can be achieved for selected frequency detunings

    Social plasticity in the fish brain: Neuroscientific and ethological aspects

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    © 2019 Elsevier B.V. Social plasticity, defined as the ability to adaptively change the expression of social behavior according to previous experience and to social context, is a key ecological performance trait that should be viewed as crucial for Darwinian fitness. The neural mechanisms for social plasticity are poorly understood, in part due to skewed reliance on rodent models. Fish model organisms are relevant in the field of social plasticity for at least two reasons: first, the diversity of social organization among fish species is staggering, increasing the breadth of evolutionary relevant questions that can be asked. Second, that diversity also suggests translational relevance, since it is more likely that “core” mechanisms of social plasticity are discovered by analyzing a wider variety of social arrangements than relying on a single species. We analyze examples of social plasticity across fish species with different social organizations, concluding that a “core” mechanism is the initiation of behavioral shifts through the modulation of a conserved “social decision-making network” along with other relevant brain regions, by monoamines, neuropeptides, and steroid hormones. The consolidation of these shifts may be mediated via neurogenomic adjustments and regulation of the expression of plasticity-related molecules (transcription factors, cell cycle regulators, and plasticity products)

    Manuseio e armazenagem seguro de produtos químicos.

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    bitstream/CPACT-2010/13146/1/folder-seg-prod-quim.pdfGestão Ambiental

    Zebrafish fin regeneration involves transient serotonin synthesis

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    The zebrafish is a vertebrate organism capable of regenerating many of its organs. Notably, it can undergo epimorphic regeneration of its fins after amputation. This process occurs through the formation of a wound epithelium and the dedifferentiation of mesenchymal and bone‐forming cells, which form a proliferative blastema. Here, we report that the entry into the regenerative process involves the local synthesis of serotonin (5‐hydroxytryptamine, 5‐HT) in the injury‐associated tissue. One day after wounding, intracellular accumulation of serotonin was induced in the stump below the amputation plane. During blastema formation, serotonin was detected in the mesenchyme at the vicinity of the amputation plane and in the apical wound epithelium. During the advanced outgrowth phase, this monoamine was no longer present in the blastema, suggesting a temporal involvement of serotonin in the postinjury area. We show the expression of two serotonin synthesizing enzymes, tryptophan hydroxylase 1a and 1b in the blastema, suggesting the local production of this monoamine. Neither depletion of serotonin by chemical inhibition of tryptophan hydroxylase, nor ectopic administration of this monoamine affected fin regeneration, indicating it does not play a role during this process. Finally, we found that the presence of serotonin during regeneration depends on fibroblast growth factor and retinoic acid signaling. Overall, our study demonstrates that the initiation of fin regeneration is associated with a transient synthesis of serotonin in the regrowing tissue

    Necesidad de adquirir competencias en aspectos legales de la educación a través de la asignatura de Legislación Educativa

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    Objetivo general: Determinar cuáles son las competencias necesarias que debe lograr el participante de la Licenciatura en Educación, a través de la asignatura de Legislación Educativa a fin de obtener profesionales capaces que puedan enfrentar los retos y exigencias de su profesión. Objetivos específicos: Definir las variables conceptualmente Competencias, Legislación Educativa). Interpretar los conocimientos previos de los estudiantes a través de una prueba diagnóstica. Diseñar instrumentos de recolección de la información. Aplicar instrumentos de recolección de la información. Evaluar la información recolectada. Dar a conocer los resultados del estudio, a las autoridades

    RAPID ESTIMATION OF GAMMA NUMBER OF VISCOSE BY UV SPECTROPHOTOMETRY

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    ABSTRACT Viscose process is the most important method for industrial cellulose dissolution. The degree of substitution (DS) is an important parameter in cellulose derivatives, and it is usually expressed as a gamma number (γ No.). In this work, viscose was prepared from eucalyptus and cotton linter dissolving pulps. Two methods were used for by-product separation: coagulation method (CM, reference) and ion exchange method (IEM). Similar γ Nos. were obtained with both methods for viscoses from cotton linters. The molar absorptivity of cellulose xanthate at 303 nm (e 303nm ) was determined by, firstly, measuring the absorbance of different purified viscoses and, subsequently, drawing a linear regression with the values obtained. The purification efficacy of IEM was analyzed from the UV peaks obtained in the range of 220-380 nm of the original and purified viscoses. The disappearance of the absorption of the main byproduct, sodium trithiocarbonate, was observed. Finally, with the e 303nm mentioned above and the absorbance measurement of the purified viscoses, their γ Nos. were determined using a spectrophotometric method (SM). This would indicate that UV spectrophotometry could be used to estimate this parameter in a quick and easy way, which is decisive for the use of viscose in regenerated cellulose products
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